Zegalogue® (dasiglucagon) injection 0.6 mg/0.6 mL Zegalogue® (dasiglucagon) injection 0.6 mg/0.6 mL
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RECOVERY TIME

FOR THE MOMENTS WHEN YOU NEED RELIABLE RESULTS

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before administration

10-MINUTE RECOVERY

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In clinical trials, median time to blood sugar recovery was 10 minutes in adults, adolescents, and children who received ZEGALOGUE® (dasiglucagon) injection. 

ZEGALOGUE® WAS EVALUATED ACROSS 3 CLINICAL TRIALS

  • ZEGALOGUE® was studied in a clinical trial program of people with type 1 diabetes
  • Two trials were conducted in adults, and a third trial was conducted in children and adolescents aged 6 years to 17 years
  • In all 3 trials, the results of participants who received ZEGALOGUE® were compared with the results of those who received placebo following insulin-induced low blood sugar
  • The primary goal in all 3 trials was to measure the time to blood sugar recovery, defined as an increase in blood sugar of at least 20 mg/dL from the time of administration, without additional intervention within 45 minutes

BLOOD SUGAR RECOVERY TRIAL RESULTS

99%

of adults in a trial

recovered within 15 minutes

In another trial, 88% of adult patients recovered within 15 minutes

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Reliable results: In adults studied recovered with a single dose

95%

of children and adolescents

recovered within 15 minutes

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Reliable results: Children and adolescents studied recovered with a single dose

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MOST COMMON SIDE EFFECTS

In clinical trials, the most common side effects of ZEGALOGUE® in adults, adolescents, and children were:

  • Nausea
  • Vomiting
  • Headache
  • Diarrhea (most common in adults only)
  • Injection site pain

See additional Important Safety Information on this page.

See how ZEGALOGUE® is designed to help you respond quickly

HOW TO USE

Indication and Important Safety Information
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What is ZEGALOGUE®?

ZEGALOGUE® (dasiglucagon) injection is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes aged 6 years and older. It is not known if ZEGALOGUE® is safe and effective in children under 6 years of age.

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Important Safety Information

Do not use ZEGALOGUE® if you:

  • have a tumor called pheochromocytoma in the gland on top of your kidneys (adrenal gland).
  • have a tumor called insulinoma in your pancreas.

Before using ZEGALOGUE®, tell your healthcare provider about all of your medical conditions, including if you:

  • have a tumor in your pancreas.
  • are allergic to dasiglucagon, or any other ingredients in ZEGALOGUE®.
  • have not had food or water for a long time (prolonged fasting or starvation).
  • have adrenal insufficiency.
  • have low blood sugar that does not go away (chronic hypoglycemia).
  • are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if ZEGALOGUE® passes into your breast milk. You and your healthcare provider should decide if you can use ZEGALOGUE® while breastfeeding.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use ZEGALOGUE®? 

  • Read the detailed Instructions For Use that come with ZEGALOGUE®.
  • Use ZEGALOGUE® exactly how your healthcare provider tells you to use it.
  • Make sure your caregiver knows where you keep your ZEGALOGUE® and how to use ZEGALOGUE® the right way before you need it.
  • Your caregiver must act quickly. Having very low blood sugar for a period of time may be harmful.
  • Your healthcare provider will tell you how and when to use ZEGALOGUE®.
  • After giving ZEGALOGUE® your caregiver should call for emergency medical help right away.
  • Once you are able to safely consume food or drink, your caregiver should give you a fast-acting source of sugar (such as fruit juice) and a long-acting source of sugar (such as crackers with cheese or peanut butter).
  • If you do not respond to treatment after 15 minutes, your caregiver may give you another dose, if available.
  • Tell your healthcare provider each time you use ZEGALOGUE®. Your healthcare provider may need to change the dose of your other diabetes medicines.

What are the possible side effects of ZEGALOGUE®?

ZEGALOGUE® may cause serious side effects, including:

  • high blood pressure. ZEGALOGUE® can cause high blood pressure in certain people with tumors in their adrenal glands.
  • low blood sugar. ZEGALOGUE® can cause certain people with tumors in their pancreas called insulinomas to have low blood sugar.
  • serious allergic reaction. Call your healthcare provider or get medical help right away if you have a serious allergic reaction including: rash, difficulty breathing, low blood pressure (hypotension).

The most common side effects of ZEGALOGUE® include: in adults: nausea, vomiting, headache, diarrhea, and injection site pain; in children: nausea, vomiting, headache, and injection site pain. These are not all the possible side effects of ZEGALOGUE®.

Please see ZEGALOGUE® Full Prescribing Information, including Patient Information.

Scroll to ISI

What is ZEGALOGUE®?

ZEGALOGUE® (dasiglucagon) injection is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes aged 6 years and older. It is not known if ZEGALOGUE® is safe and effective in children under 6 years of age.

What is ZEGALOGUE®?

ZEGALOGUE® (dasiglucagon) injection is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes aged 6 years and older. It is not known if ZEGALOGUE® is safe and effective in children under 6 years of age.

Important Safety Information

Do not use ZEGALOGUE® if you:

  • have a tumor called pheochromocytoma in the gland on top of your kidneys (adrenal gland).
  • have a tumor called insulinoma in your pancreas.

Before using ZEGALOGUE®, tell your healthcare provider about all of your medical conditions, including if you:

  • have a tumor in your pancreas.
  • are allergic to dasiglucagon, or any other ingredients in ZEGALOGUE®.
  • have not had food or water for a long time (prolonged fasting or starvation).
  • have adrenal insufficiency.
  • have low blood sugar that does not go away (chronic hypoglycemia).
  • are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if ZEGALOGUE® passes into your breast milk. You and your healthcare provider should decide if you can use ZEGALOGUE® while breastfeeding.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use ZEGALOGUE®? 

  • Read the detailed Instructions For Use that come with ZEGALOGUE®.
  • Use ZEGALOGUE® exactly how your healthcare provider tells you to use it.
  • Make sure your caregiver knows where you keep your ZEGALOGUE® and how to use ZEGALOGUE® the right way before you need it.
  • Your caregiver must act quickly. Having very low blood sugar for a period of time may be harmful.
  • Your healthcare provider will tell you how and when to use ZEGALOGUE®.
  • After giving ZEGALOGUE® your caregiver should call for emergency medical help right away.
  • Once you are able to safely consume food or drink, your caregiver should give you a fast-acting source of sugar (such as fruit juice) and a long-acting source of sugar (such as crackers with cheese or peanut butter).
  • If you do not respond to treatment after 15 minutes, your caregiver may give you another dose, if available.
  • Tell your healthcare provider each time you use ZEGALOGUE®. Your healthcare provider may need to change the dose of your other diabetes medicines.

What are the possible side effects of ZEGALOGUE®?

ZEGALOGUE® may cause serious side effects, including:

  • high blood pressure. ZEGALOGUE® can cause high blood pressure in certain people with tumors in their adrenal glands.
  • low blood sugar. ZEGALOGUE® can cause certain people with tumors in their pancreas called insulinomas to have low blood sugar.
  • serious allergic reaction. Call your healthcare provider or get medical help right away if you have a serious allergic reaction including: rash, difficulty breathing, low blood pressure (hypotension).

The most common side effects of ZEGALOGUE® include: in adults: nausea, vomiting, headache, diarrhea, and injection site pain; in children: nausea, vomiting, headache, and injection site pain. These are not all the possible side effects of ZEGALOGUE®.

Please see ZEGALOGUE® Full Prescribing Information, including Patient Information.

What is ZEGALOGUE®?

ZEGALOGUE® (dasiglucagon) injection is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes aged 6 years and older. It is not known if ZEGALOGUE® is safe and effective in children under 6 years of age.

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ZEGALOGUE® is a registered trademark of Novo Nordisk A/S.
Novo Nordisk is a registered trademark of Novo Nordisk A/S.
All other trademarks, registered or unregistered, are the property of their respective owners.
© 2024 Novo Nordisk  All rights reserved.  US23ZGL00030  February 2024

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