Zegalogue® (dasiglucagon) injection 0.6 mg/0.6 mL Zegalogue® (dasiglucagon) injection 0.6 mg/0.6 mL

Find confidence in being prepared. Get to know ZEGALOGUE®  (dasiglucagon) injection

ZEGALOGUE was evaluated across 3 clinical trials

STUDIES INCLUDED ADULTS, ADOLESCENTS, AND CHILDREN

ZEGALOGUE was studied in a clinical trial program of people with type 1 diabetes. Two trials were conducted in adults, and a third trial was conducted in children and adolescents aged 6 to 17 years. In all 3 trials, the results of participants who received ZEGALOGUE were compared with the results of those who received a placebo following insulin-induced low blood sugar. 

The primary goal in all 3 trials was to measure the time to blood sugar recovery, defined as an increase in blood sugar of at least 20 mg/dL from the time of administration, without additional intervention. 

ZEGALOGUE provided consistent results when needed

RAPID RECOVERY

In clinical trials, median time to blood sugar recovery was 10 minutes in adults, adolescents, and children.

BLOOD SUGAR RECOVERY IN A TRIAL OF ADULTS

99%

of adults recovered in 15 minutes

Reliable results: adults studied recovered with a single dose

In another trial, 88% of adult patients recovered in 15 minutes.

BLOOD SUGAR RECOVERY IN A TRIAL OF CHILDREN AND ADOLESCENTS

95%

of children and adolescents recovered in 15 minutes

Reliable results: children and adolescents studied recovered with a single dose

Most common side effects

In clinical trials, the most common side effects of ZEGALOGUE in adults were: 

  • Nausea
  • Vomiting
  • Headache
  • Diarrhea
  • Injection site pain

In clinical trials, the most common side effects of ZEGALOGUE in children and adolescents were: 

  • Nausea
  • Vomiting
  • Headache
  • Injection site pain 

For very low blood sugar, you can rely on ZEGALOGUE

Learn how you can be ready to treat very low blood sugar

HOW TO BE ZEGALOGUE-READY

Indication and Important Safety Information
Read More Collapse

What is ZEGALOGUE®?

ZEGALOGUE® (dasiglucagon) injection is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes aged 6 years and older. It is not known if ZEGALOGUE® is safe and effective in children under 6 years of age.

Scroll to Indication

Important Safety Information

Do not use ZEGALOGUE® if you:

  • have a tumor called pheochromocytoma in the gland on top of your kidneys (adrenal gland).
  • have a tumor called insulinoma in your pancreas.

Before using ZEGALOGUE®, tell your healthcare provider about all of your medical conditions, including if you:

  • have a tumor in your pancreas.
  • are allergic to dasiglucagon, or any other ingredients in ZEGALOGUE®.
  • have not had food or water for a long time (prolonged fasting or starvation).
  • have adrenal insufficiency.
  • have low blood sugar that does not go away (chronic hypoglycemia).
  • are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if ZEGALOGUE® passes into your breast milk. You and your healthcare provider should decide if you can use ZEGALOGUE® while breastfeeding.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use ZEGALOGUE®? 

  • Read the detailed Instructions For Use that come with ZEGALOGUE®.
  • Use ZEGALOGUE® exactly how your healthcare provider tells you to use it.
  • Make sure your caregiver knows where you keep your ZEGALOGUE® and how to use ZEGALOGUE® the right way before you need it.
  • Your caregiver must act quickly. Having very low blood sugar for a period of time may be harmful.
  • Your healthcare provider will tell you how and when to use ZEGALOGUE®.
  • After giving ZEGALOGUE® your caregiver should call for emergency medical help right away.
  • Once you are able to safely consume food or drink, your caregiver should give you a fast-acting source of sugar (such as fruit juice) and a long-acting source of sugar (such as crackers with cheese or peanut butter).
  • If you do not respond to treatment after 15 minutes, your caregiver may give you another dose, if available.
  • Tell your healthcare provider each time you use ZEGALOGUE®. Your healthcare provider may need to change the dose of your other diabetes medicines.

What are the possible side effects of ZEGALOGUE®?

ZEGALOGUE® may cause serious side effects, including:

  • high blood pressure. ZEGALOGUE® can cause high blood pressure in certain people with tumors in their adrenal glands.
  • low blood sugar. ZEGALOGUE® can cause certain people with tumors in their pancreas called insulinomas to have low blood sugar.
  • serious allergic reaction. Call your healthcare provider or get medical help right away if you have a serious allergic reaction including: rash, difficulty breathing, low blood pressure (hypotension).

The most common side effects of ZEGALOGUE® include: in adults: nausea, vomiting, headache, diarrhea, and injection site pain; in children: nausea, vomiting, headache, and injection site pain. These are not all the possible side effects of ZEGALOGUE®.

Please see ZEGALOGUE® Full Prescribing Information, including Patient Information.

Scroll to ISI

What is ZEGALOGUE®?

ZEGALOGUE® (dasiglucagon) injection is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes aged 6 years and older. It is not known if ZEGALOGUE® is safe and effective in children under 6 years of age.

What is ZEGALOGUE®?

ZEGALOGUE® (dasiglucagon) injection is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes aged 6 years and older. It is not known if ZEGALOGUE® is safe and effective in children under 6 years of age.

Important Safety Information

Do not use ZEGALOGUE® if you:

  • have a tumor called pheochromocytoma in the gland on top of your kidneys (adrenal gland).
  • have a tumor called insulinoma in your pancreas.

Before using ZEGALOGUE®, tell your healthcare provider about all of your medical conditions, including if you:

  • have a tumor in your pancreas.
  • are allergic to dasiglucagon, or any other ingredients in ZEGALOGUE®.
  • have not had food or water for a long time (prolonged fasting or starvation).
  • have adrenal insufficiency.
  • have low blood sugar that does not go away (chronic hypoglycemia).
  • are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if ZEGALOGUE® passes into your breast milk. You and your healthcare provider should decide if you can use ZEGALOGUE® while breastfeeding.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use ZEGALOGUE®? 

  • Read the detailed Instructions For Use that come with ZEGALOGUE®.
  • Use ZEGALOGUE® exactly how your healthcare provider tells you to use it.
  • Make sure your caregiver knows where you keep your ZEGALOGUE® and how to use ZEGALOGUE® the right way before you need it.
  • Your caregiver must act quickly. Having very low blood sugar for a period of time may be harmful.
  • Your healthcare provider will tell you how and when to use ZEGALOGUE®.
  • After giving ZEGALOGUE® your caregiver should call for emergency medical help right away.
  • Once you are able to safely consume food or drink, your caregiver should give you a fast-acting source of sugar (such as fruit juice) and a long-acting source of sugar (such as crackers with cheese or peanut butter).
  • If you do not respond to treatment after 15 minutes, your caregiver may give you another dose, if available.
  • Tell your healthcare provider each time you use ZEGALOGUE®. Your healthcare provider may need to change the dose of your other diabetes medicines.

What are the possible side effects of ZEGALOGUE®?

ZEGALOGUE® may cause serious side effects, including:

  • high blood pressure. ZEGALOGUE® can cause high blood pressure in certain people with tumors in their adrenal glands.
  • low blood sugar. ZEGALOGUE® can cause certain people with tumors in their pancreas called insulinomas to have low blood sugar.
  • serious allergic reaction. Call your healthcare provider or get medical help right away if you have a serious allergic reaction including: rash, difficulty breathing, low blood pressure (hypotension).

The most common side effects of ZEGALOGUE® include: in adults: nausea, vomiting, headache, diarrhea, and injection site pain; in children: nausea, vomiting, headache, and injection site pain. These are not all the possible side effects of ZEGALOGUE®.

Please see ZEGALOGUE® Full Prescribing Information, including Patient Information.

What is ZEGALOGUE®?

ZEGALOGUE® (dasiglucagon) injection is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes aged 6 years and older. It is not known if ZEGALOGUE® is safe and effective in children under 6 years of age.


Zegalogue® is a registered trademark of Novo Nordisk A/S.
Novo Nordisk is a registered trademark of Novo Nordisk A/S.
All other trademarks, registered or unregistered, are the property of their respective owners.
© 2022 Novo Nordisk   All rights reserved.   US22ZGL00010   December 2022

Continue
Continue
Access Resources